Be sure to communicate your ETA with the seller and notify them if anything changes.
Bring along appropriate strapping equipment and supplies for securing the load. Keep necessary paperwork with you. Check air pressure in all your tires to ensure they are at proper levels.
Watch the Weather
If hauling an uncovered load, watch the weather and have a tarp along if needed.
Be aware of the state's DOT laws in which you will be hauling.
Know Your Weights
Be sure you know your unloaded weight and your maximum GVWR to ensure you will not be overloaded.